Chemistry is regarded as heart of all the scientific disciplines. For long time in the last century, chemical industries had been considered even as index of national development. In this context, the history of Chemistry Education in our country is relatively new. The teaching of Chemistry in Nepal commenced in 1921 in Tri-Chandra College, with the introduction of Intermediate of Science (I. Sc.) program, which was then upgraded to Bachelor of Science (B. Sc.) level in 1947. Tribhuvan University (TU) named after the late king Tribhuvan, was established by promulgating the Tribhuvan University Act in July 14, 1959. Master’s Degree in Chemistry was started only from December 1965 initially at Tri-Chandra College with the introduction of a program in Organic Chemistry. This historical step also pioneered the introduction of research initiatives in Chemistry in Nepal. Late Professor Prasanna Man Singh Pradhan was the first the Lecturer-in-Charge of the Master’s program.